Page 9 - SLIDES
P. 9
VESPER Commentary
• ddMVAC as new SOC for NAC
• Number of cycles of chemo
• Should we use 6 cycles for NAC?
• Toxicity: Only 60% of ddMVAC patients received 6 cycles
(84% received 4 cycles of Gem/Cis)
• Toxicity and pathological response reported by Pfister et al, Eur
Urol 2021 (February)
• Other points:
• ddMVAC as SOC based on secondary outcome?
• Primary outcome not met
• 3 yr PFS is a more clinically important endpoint than pCR