Page 8 - Flipbook
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Platinums are the backbone of first-line therapy in aUC
Gemcitabine-Cisplatin (GC): Median OS ~ 14 mos, ddMVAC: Median OS ~ 15 mos
Gemcitabine-Carboplatin: Recent trials show median OS~ 13 mos
nd
Only a minority of patients receive 2 -line therapy for mUC
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An unmet need to improve survival with 1 -line treatment
Von der Maase H et al. JCO 2005 Sternberg CN Eur J Cancer 2006, Galsky MD Lancet 2020, Flannery K et al. Future Oncol 2019, Powles T ASC) GU 2021
