Page 15 - PRESENTATION
P. 15

What Is BCG-unresponsive NMIBC?











               1. Any high grade recurrence after induction +

                            Ta/CIS: failure to achieve CR at 6 months
                         1 round maintenance, or 2 rounds induction
                             st





                       – Exception: high grade T1 disease after induction BCG
                                   T1: failure to achieve CR at 3 months
                                                          only is considered “unresponsive”




               2. For patients who achieve complete response on



                        Relapse: high grade recurrence within 6-12
                         induction/maintenance BCG: any high gradeTa/T1


                          months of last dose of BCG after prior CR
                         recurrence within 6 months of last dose of BCG,



                         or CIS within 12 months of last dose
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