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Multidisciplinary Management

                                of Bladder Cancer



                                                                                          Diagnosis Tool








                                     Suspected MIBC



                               Patient history and physical exam




                                    High quality TURBT                   Histology      Histological type (including mixed histologies)
                                                                                        e.g. urothelial, squamous, small cell carcinoma

                                                                       Depth of Invasion  Depth of tumor invasion into muscularis propria
               Referal to patient
                information
                 resources         Imaging, Pathology,                    Grade                    High/Low
              (e.g. Bladder Cancer   Staging & Resectability
                 Canada)
                                                                      Concomitant CIS/ LVI  Evaluation of tumour dissemination/metastasis



               Assess need for    Hydronephrosis                         Divergent
               renal drainage                                          differentiation of   Include variant histology/proportion of variant histology
                                                                      urothelial carcinoma


                                            Metastatic



                           YES                                    NO




                    Significant local symptoms    YES  Assemble multidisciplinary care conference
                     or recurrent hematuria

                           NO


                 Direct referal to medical oncologist











             Contributing Authors:  Abbreviations:                 References:
             Aly-Khan Lalani, MD, FRCPC    CIS    carcinoma in situ  Kulkarni et al., Canadian Urological Association guideline: Muscle-invasive bladder cancer, CUAJ. (2019).
             Wassim Kassouf, MD, CM, FRCSC  LVI    lymphovascular invasion
                                    MIBC   muscle-invasive bladder cancer
                                    TURBT  transurethral resection of bladder tumour
                                                                                         Canadian Urological Association. All rights reserved. October 2022
             This tool card has been made possible through funding from Bristol-Myers Squibb in the form of an educational grant.  BC-MANAGEMENT-Eng-1500-Oct.2022
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