Page 8 - CUA2019 Abstracts - Oncology-Bladder

Poster session 2: bladder Cancer

UP-2.9 each patient. Multivariable analyses were used to determine the asso-
Venous thromboembolism and transfusion following major ciation between individual procedures and VTE. Area under the curve
abdominopelvic surgery (AUC) analyses were performed to assess whether the addition of surgical
2
1,2
1
2,3
Kristen McAlpine , Rodney H. Breau , Christopher Knee , Marc Carrier , procedure to Caprini score improved the ability of the model to predict
Philippe Violette , Carl van Walraven , Dan I. McIsaac , Ranjeeta VTE. The primary outcome was risk of VTE within 30 days of surgery.
2,3
4
2,5
1,2
Mallick , Ilias Cagiannos , Christopher Morash , Luke T. Lavallée 1,2 Secondary outcomes were the risk of transfusion within 30 days and the
2
1,2
1 Division of Urology, The Ottawa Hospital, Ottawa, ON, Canada; association between operative time and VTE.
3
2 Ottawa Hospital Research Institute, Ottawa, ON, Canada; Department Results: There were 896 441 patients who received an abdominopelvic
4
of Medicine, The Ottawa Hospital, Ottawa, ON, Canada; Departments procedure during the study period. The overall risk of VTE was 1.9%
of Health Research Methods Evidence and Impact and Surgery, McMaster (n=16 665). Urological procedures with the highest risk of VTE were
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University, Hamilton, ON, Canada; Departments of Anesthesiology & radical cystectomy (4.3%) and open nephrectomy (2.4%). The overall
Pain Medicine, The Ottawa Hospital, Ottawa, ON, Canada risk of transfusion was 9.5% (n=84 889). Urological procedures with the
Funding: University of Ottawa Department of Surgery Research Program highest risk of transfusion were radical cystectomy (37.7%) and open
Award nephrectomy (27.2%). On multivariable analyses, individual procedures
Introduction: Thromboprophylaxis aims to reduce venous thromboem- were independently associated with VTE despite adjusting for the Caprini
bolism (VTE) but has the potential to increase bleeding. We sought to score. AUC analyses indicated risk-prediction of the baseline model
evaluate the risk of VTE and transfusion following major abdominopelvic (Caprini score AUC 0.59) improved when surgical procedures were
procedures and to quantify the independent risk of procedure on VTE. added (AUC 0.68).
Methods: The American College of Surgeons’ National Surgical Quality Conclusions: Patients undergoing abdominopelvic surgery are at high risk
Improvement Program was queried for patients who received an abdomi- of VTE and transfusion. Improved risk-stratification may be possible by
nopelvic surgery from 2005–2016. Patient factors, operative factors, and including more procedural information in scoring systems or by creating
outcomes were collected. A modified Caprini score was calculated for scoring systems that incorporate procedures’ baseline VTE risk.

S95 CUAJ • June 2019 • Volume 13, Issue 6(Suppl5) S95
CUAJ • June 2019 • Volume 13, Issue 6(Suppl5)