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2020 CUA Abstracts






         POD-1.1. Table 1B. Number of subjects with urologic events by year 1 (adjudicated by CEC)
                                                                   Treatment
                                                    Aquablation                    TURP
         Event summary                           n         Rate per 100      n         Rate per 100     p*
         Bladder neck contracture                3            2.6            1             1.5          1
         Bladder pain/spasm                      7             6             3             4.6          1
         Bleeding                                17           14.7           10           15.4        1.0000
         Decreased libido                        0             0             1             1.5        0.3591
         Dysuria                                 15           12.9           6             9.2        0.6293
         Erectile dysfunction                    0             0             1             1.5        0.3591
         Non-urological                          2            1.7            4             6.2        0.1898
         Pain                                    8            6.9            4             6.2        1.0000
         Penile edema                            1            0.9            0             0            1
         Penile trauma                           1            0.9            0             0            1
         Prostate cancer                         0             0             1             1.5        0.3591
         Retrograde ejaculation                  8            6.9            17           26.2        0.0006
         Stricture or adhesions                  3            2.6            3             4.6        0.6684
         Swollen testicles                       0             0             1             1.5        0.3591
         Urethral damage                         1            0.9            1             1.5          1
         Urinary retention                       10           8.6            7            10.8        0.6085
         Urinary tract infection                 13           11.2           8            12.3        0.8133
         Urinary tract stones                    0             0             2             3.1        0.1277
         Urinary urgency/frequency/difficulty/   20           17.2           9            13.8        0.6740
         leakage
         *Fisher’s test p value.

        POD-1.2                                              Conclusions: The incidence of surgically treated PUL is stable over 15
        Surgical trends in pediatric urolithiasis management in Ontario   years in Ontario, Canada. URS has become the most common surgical
        from 2002–2016                                       treatment modality for PUL and ESWL rates have dropped, possibly sec-
                                                         1
                          1
        Fernanda Gabrigna Berto , Zhan Tao (Peter) Wang , Jennifer Bjazevic ,   ondary to the higher rates of re-do surgical intervention.
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        Guido Filler , Blayne K. Welk , Hassan Razvi , Sumit Dave 1  References
                            1
                                                   2
        1 Urology, University of Western Ontario, London, ON, Canada;  Pediatric   1.   Alfandary H, Haskin O, Davidovits M, et al. Increasing prevalence
        Nephrology, University of Western Ontario, London, ON, Canada  of nephrolithiasis in association with increased body mass index in
        Introduction: A global increase in pediatric urolithiasis (PUL) incidence   children: A population-based study. J Urol 2018;199:1044-9. https://
        has been reported.  As a potentially recurrent condition, PUL has   doi.org/10.1016/j.juro.2017.10.023
                      1-5
        implications on morbidity  and healthcare costs. This study evaluates   2.   Park HK, Kim JH, Min GE, et al. Change of trends in the treatment
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                          5,6
        surgical trends and outcomes of PUL in Ontario over a 15 year-period   modality for pediatric nephrolithiasis: Retrospective analysis of a
        (2002–2016).                                             U.S.-based insurance claims database. J Endourol 2019;33:614-8.
        Methods: This retrospective cohort study used administrative databases   https://doi.org/10.1089/end.2019.0154
        held at the Institute of Clinical Evaluative Sciences to identify all children   3.   Sas DJ, Hulsey TC, Shatat IF, et al. Increasing incidence of kidney
        (<18 years) who underwent their first surgical treatment for PUL using the   stones in children evaluated in the emergency department. J Pediatr
        Canadian Institute for Health Information-Discharge Abstract Database   2010;157:132-7. https://doi.org/10.1016/j.jpeds.2010.02.004
        and ICD10th revision. Stone location and treatment modality were simul-  4.   Matlaga BR, Schaeffer AJ, Novak TE, et al. Epidemiologic insights
        taneously identified. Descriptive statistics were used to summarize patient   into pediatric kidney stone disease. Urol Res 2010;38:453-7. https://
        demographics and surgical trends. Logistic regression analysis was per-  doi.org/10.1007/s00240-010-0327-
        formed to identify independent risk factors for repeat surgical intervention   5.   Routh JC, Graham DA, Nelson CP. Epidemiological trends in pedi-
        within six months of index procedure.                    atric urolithiasis at United States freestanding pediatric hospitals. J
        Results: A total of 706 patients undergoing surgical procedure for PUL   Urol 2010;184:1100-4. https://doi.org/10.1016/j.juro.2010.05.018
        were identified (mean age 12.6±4.8 years); 68.5% of children were older   6.   Schaeffer AJ, Feng Z, Trock BJ, et al. Medical comorbidities associ-
        than 12 years and 55.2% presented with ureteric stones. There was no   ated with pediatric kidney stone disease. Urology 2011;77:195-9.
        statistical increase in the number of procedures performed, gender pre-  https://doi.org/10.1016/j.urology.2010.06.062
        dominance, or age difference at surgery. Ureteroscopy (URS) was the most   7.   Kusumi K, Becknell B, Schwaderer A. Trends in pediatric urolithiasis:
        commonly performed procedure (63.7%) and its application increased   Patient characteristics, associated diagnoses, and financial burden.
        over time (p<0.0001) (Fig. 1). Conversely, extracorporeal shockwave litho-  Pediatr Nephrol 2015;30:805-10. https://doi.org/10.1007/s00467-
        tripsy (ESWL) use decreased. Percutaneous nephrolithotripsy rates (9.6%)   014-3012-3
        were stable. Renal stone location (odds ratio [OR] 2.79; p=0.0002) and
        ESWL (OR 1.66; p=0.0025) were independent risk factors for repeat surgi-
        cal procedure within six months. Stone recurrence requiring additional
        surgery after five years was 33%.
        S24                                     CUAJ • June 2020 • Volume 14, Issue 6(Suppl2)
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