Page 10 - Flipbook

Olaparib in mCRPC / Treatment Sequencing

Treatment not
yet received
ADT + ARAT Docetaxel or Radium or
nmCRPC Progress to Progress
mCRPC Olaparib
Olaparib if HRRm if HRRm

Treatment not
yet received
or

ADT + Docetaxel Progress to Abi or Enza Progress Olaparib

mCRPC CBZ or Radium if HRRm

Metastatic
Treatment not
CSPC or CRPC ADT + ARAT Progress to Docetaxel or Radium yet received
or
Progress
mCRPC Olaparib if HRRm Olaparib

if HRRm

Choice based on Level 1 evidence
Personal slide Saad F : Adapted CUA guidelines for CRPC 2021, CUAJ 2021