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Theranostics: diagnostics + therapy based on 8
the same molecular target
Molecular Ligand Therapeutic Imaging
target isotope isotope
Imaging radiation Therapeutic radiation
Annihilation with tissue DNA damage → cell death
electrons→ γ-ray production Auger
α
ß
+
TUMOR ß
-
-
PET Imaging (ß ) ► therapeutic radiation (Auger, α or ß ) Ong JS,
+
RSNA 2021
