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TREATMENT OPTIONS FOR ADULT OAB – CUA GUIDELINES








                                                                    Behavioural therapies, lifestyle changes, education

                       FIRST LINE                                        Fluid/caffeine/dietary modification, weight control,
                                                          management of bowel regularity, optimization of comorbidities, exercise,
                                                                smoking cessation, bladder training, pelvic floor muscle training






                                                                                  Pharmacological management:
                                                      • Antimuscarinics (oxybutynin, tolterodine, darifenacin, trospium, solifenacin,
                       SECOND LINE                       propiverine, fesoterodine)

                                                      • -3 adrenoceptor agonist (mirabegron)








                                                     Onabotulinumtoxin                          Posterior tibial                             Sacral
                       THIRD LINE                                  A                          nerve stimulation                      neuromodulation

                                                             (BoNT-A)                                 (PTNS)                                 (SNM)







                                                         Indwelling catheters, augmentation cystoplasty, urinary diversion




                                                                                                                                            Corcos J, et al. Can Urol Assoc J 2017;11:E142-73
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