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PSMA PET

• aka glutamate carboxypeptidase II

• Folate metabolism

• Neuronal signaling

Extracellular
• Overexpressed in prostate cancer Domain

Site of
• Level of PSMA expression correlates PSMA

with tumour stage and tumor grade Inhibitor

• Examples of commonly used PSMA Transmembrane
Domain
agents include F-18 PyL, F-18 1007 and

Ga-68 PSMA-11 Intracellular

Domain

Barrio, M., Expt Rev. Mol. Diagn. 2016; 16(11):1177-1188.
Tateishi, U., Jpn. J. Clin. Oncol. 2020; 50(4):349-356

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