Page 13 - Poster Sessions] CUA 2022 Annual Meeting Abstracts
P. 13

Poster 2: BPH






         MP-2.15. Table 1. Perioperative hemoglobin and sodium levels after monopolar TURP and GreenLight laser PVP
         Variable                Monopolar TURP (glycine 1.5%)  Greenlight laser PVP (normal saline)  Mean diff (95% CI)  p
         Patients                690 (70.8%)               284 (29.2%)
         Pre-op Hb, mean ± SD    140.7±16.8                137.5±17.6                                   0.02
         Post-op Hb, mean ± SD   128.7±18.0                128.1±19.4                                   0.65
         Ref range: 130–170 g/L
         Hb change, mean ± SD    -8.7±10.7                 -4.1±19.1                    4.6 (1.7–7.6)   0.002
         Pre-op Na, mean ± SD    141.0±2.7                 140.6±3.2                                    0.51
         Post-op Na, mean ± SD   138.1±3.9                 138.6±3.4                                    0.17
         Ref range: 135–145 mmol/L
         Na change, mean ± SD    -2.8±4.0                  -1.9±3.9                     1.0 (0.1–1.9)   0.03

        UP-2.3                                               Introduction: 5-alpha reductase inhibitors (5-ARIs) are an effective med-
        Impact of 5-alpha reductase inhibitors on functional outcomes of   ical therapy for patients with lower urinary tract symptoms due to benign
        GreenLight photovaporization of the prostate (PVP): An analysis   prostatic hyperplasia (BPH). Furthermore, they can cause alterations in
        of 3500 men in the Global GreenLight Group (GGG) database  various prostate tissue parameters. We sought to investigate the impact of
        Iman Sadri , David-Dan Nguyen , Kyle Law , Adel Arezki , David
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                1
        Bouhadana , Naeem Bhojani , Dean Elterman , Ahmed S. Zakaria , Franck
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                                                    5
                                       4
                2
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                        7
              6
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        Bruyère , Luca Cindolo , Giovanni Ferrari , Carlos Vasquez-Lastra  , Tiago   UP-2.3. Table 2. Unadjusted functional and perioperative
                                        11
                 9
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        Borelli-Bovo  , Edgardo F Becher , Hannes Cash , Maximillian Reimann ,   outcomes
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                 12
        Enrique Rijo , Vincent Misrai , Kevin Zorn 3
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        1 Division of Urology, McGill University Health Centre, Montreal, QC,       Control    5-ARI      p
              2
        Canada;  Faculty of Medicine, McGill University, Montreal, QC, Canada;   Operation time, min, mean   67.82 (30.68) 69.93 (32.66) 0.07
        3 Division of Urology, Centre Hospitalier de l’Université de Montréal   (SD)
                               4
        (CHUM), Montreal, QC, Canada;  Division of Urology, University Health   Lasing time, min, mean   38.5 (22.19)  38.1 (21.23)  0.63
                               5
        Network, Toronto, ON, Canada;  Division of Urology, Northern Ontario   (SD)
                                        6
        School of Medicine, Thunder Bay, ON, Canada;  Department of Oncology
        and Urology, Centre Hospitalier Universitaire de Tours, Tours, France;   Energy, kJ, mean (SD)  132.5   87.84   <0.01
        7 Department of Urology, Hesperia Hospital, Modena, Italy;  Department      (196.14)   (152.55)
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        of Urology, ABC Medical Center, Mexico City, , Mexico;  Borelli Urologia,   Number of fibers, median   1.00 (1.00–  1.00 (1.00–  0.4
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        Ribeirão Presto, Sao Paulo, Brazil;  Centro de Urologia, CDU, Buenos   (IQR)  1.00)    1.00)
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                    11
        Aires, Argentina;  Department of Urology, Charité – Universitaetsmedizin
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        Berlin, Berlin, Germany;  Department of Urology, Hospital Quiron   Hospital stay, days, median  2.00 (1.00–  1.00 (1.00–  <0.01
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        Barcelona, Barcelona, Spain;  Department of Urology, Clinique Pasteur,   (IQR)  3.00)  2.00)
        Toulouse, France                                       Transfusion rate, n (%)  14 (0.86)  8 (0.79)  0.04
                                                               Hematuria rate, n (%)  129 (9.96)  83 (9.52)  0.12
                                                               30-day readmission rate,   108 (13.42)  79 (12.46)  0.29
         UP-2.3. Table 1. Baseline patient demographics        n (%)
                             Control    5-ARI      p-value     IPSS decrease at 6 months,  16.22 (7.40)  17.01 (7.06)  0.03
                             (n=2254)   (n=1246)               mean (SD)
          Age, years, mean (SD)  70.11 (9.05)  70.72 (8.61)  0.06  IPSS decrease at 12   18.02 (7.58)  18.08 (7.21)  0.88
          TRUS volume, ml, mean  71.50 (36.36) 73.95 (38.37)  0.07  months, mean (SD)
          (SD)                                                 QoL decrease at 6 months,   3.32 (1.56)  3.51 (1.38)  0.49
          ASA score, n (%)                         <0.01       mean (SD)
           1                 246 (10.9)  185 (14.8)            QoL decrease at 12 months,  3.44 (1.92)  3.72 (1.34)  0.09
           2                 610 (27.1)  430 (34.5)            mean (SD)
           3+                1398 (62.0)  631 (50.6)           PSA decrease at 6 months,   2.19 (8.46)  0.75 (52.08)  0.4
          IPSS, mean (SD)    22.57 (6.61)  23.36 (6.53)  <0.01  ng/ml, mean (SD)
          QOL, mean (SD)     3.74 (1.93)  4.35 (1.50)  <0.01   PSA decrease at 12 months,  2.06 (5.43)  1.15 (27.13)  0.41
                                                               ng/ml, mean (SD)
          PSA, ng/dl, mean (SD)  8.08 (48.85)  4.99 (18.9)  0.04  PVR decrease at 6 months,   251.47   224.45   0.13
          PVR, ml, mean (SD)  202.67    225.77     0.06        ml, mean (SD)        (304.87)   (232.12)
                             (284.27)   (238.16)               PVR decrease at 12 months,  259.31   226.3   0.09
          Qmax, ml/s, mean (SD)  7.41 (4.16)  6.62 (3.62)  <0.01  ml, mean (SD)     (304.14)   (235.58)
          α-blocker use, n (%)                     <0.01       Qmax change at 6 months,  +11.96 (7.09) +12.78 (6.79) 0.09
           Yes               1626 (72.1)  1106 (88.8)          ml/s, mean (SD)
           No                618 (27.4)  140 (11.2)            Qmax change at 12 months,  +11.90 (6.96) +13.01 (6.68) 0.03
           Unknown           10 (0.4)   0 (0)                  ml/s, mean (SD)
                                                CUAJ • June 2022 • Volume 16, Issue 6(Suppl1)                S35
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