Page 10 - Flipbook

PERSONALIZING ADT: MANY FACTORS INFLUENCE CHOICE

• T suppression profile • Concomitant therapies

• Adverse events e.g. anti-coagulants

• Compliance • Muscle mass

• Injection features • Wheelchair-user

• Site • Intermittent therapy

• SC vs. IM • Patients with M0 CSPC, moderate risk

• Local injection reactions of progression and good initial
response to ADT
• Dosing intervals • Patients with low burden of metastases

• Comorbidities (including and complete response to ADT

concomitant CV disease) • Cost

• Drug-drug interactions • Lifestyle

CSPC Castration sensitive prostate cancer IM Intramuscular SC Subcutaneous T Testosterone