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STAMPEDE: docetaxel overall survival by

disease burden 1,2

Low Burden High Burden

HR 0.76 5-yr HR 0.81 5-yr

95% CI 0.54 – 1.07 survival: 95% CI 0.64 – 1.02 survival:
P = 0.107 A 57% P = 0.064 A 24%
Non-PH 0.809 C 72% Non-PH 0.251 C 34%

CI, confidence interval; Doc, docetaxel; FPM, flexible parametric model; HR, hazard ratio; PH, proportional hazards; SOC, standard of care; trt, treatment.
1. Clarke NW, et al. Ann Oncol. 2019;30(12):1992–2003; 2. Clarke NW, et al. Poster at the 2019 ESMO Congress; September 27–October 1, 2019; Barcelona, Spain.