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PATRON






                Primary Outcome Measures:


                              failure-free survival (FFS)




                Secondary Outcome Measures:


                              Rates of toxicity (CTCAE)


                              Time to subsequent next-line therapy



                              Quality of Life (EPIC 26)


                              New lesion detection yield (on PSMA PET/CT)


                              Impact of PMSA PET/CT on RT or surgical management (rate of

                              treatment intensification)


                              Cost-effectiveness (EQ5D5L)
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