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Prostate Cancer Epidemiology
• 1 in 7 lifetime risk
• Risk factors: age, race, family history
• Family history remains strong risk-factor
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– 1 Degree relative: RR = 2.0
– 1 Degree relative <65: RR = 3.4
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– 2 1 Degree relatives: RR = 4.39
• Estimated “genetic factors” can explain 58% of prostate cancer risk
Mucci, JAMA 2016