Page 7 - Flipbook
P. 7

Germline vs. Somatic Genetics








































                                                      •     Present in every cell in body              •     Only present in the tumour
                                                      •     Fixed (present throughout life) •                Variable (can change over time)

                                                      •     Passed on to offspring                     •     Not passed on to offspring
                                                      •     Obtained via sputum/blood                  •     Obtained via biopsy

                                                      •     E.g. BRCA mutation                         •     E.g. PTEN loss
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