Page 7 - Flipbook
P. 7
Germline vs. Somatic Genetics
• Present in every cell in body • Only present in the tumour
• Fixed (present throughout life) • Variable (can change over time)
• Passed on to offspring • Not passed on to offspring
• Obtained via sputum/blood • Obtained via biopsy
• E.g. BRCA mutation • E.g. PTEN loss