Page 18 - CUA KIDNEY CANCER HANDBOOK 2020

IMDC (International Metastatic Renal Cell Carcinoma
Database Consortium) Criteria for Prognosis in mRCC
(Heng 2009/2013)

Criterion No (0) / Yes (+1)

<1 year from time of diagnosis to systemic therapy 0 / 1
Karnofsky Performance Status <80% 0 / 1

Hemoglobin < lower limit of normal 0 / 1
Corrected calcium > upper limit of normal 0 / 1
Neutrophils > upper limit of normal 0 / 1

Platelets > upper limit of normal 0 / 1
Number of criteria

Number of criteria Risk Group Median overall survival

0 Favourable 43.2 months (95%CI: 31.4-50.1)
1-2 Intermediate 22.5 months (95%CI: 18.7-25.1)

3-6 Poor 7.8 months (95%CI: 6.5-9.7)

An online calculator can be found at IMDConline.com

12 Practical Approaches to Managing Advanced Kidney Cancer