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Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guidelines
• Developed-written by a team of Clinicians/Researchers (12).
• First step: the team generated several key questions in male infertility
evaluation and treatment (did not build on previous guideline - 2015).
• Second Step: A separate (independent) team (ECRI Institute)
performed a literature search and analysis of the data to help
provide recommendations on the Key questions. High-quality studies
were given preference: Prospective and RCTs
• Established 52 Guideline statements, directive and non-directive
• Strength rating based on the level of evidence (A-High, B-Moderate,
C-Low)
• A Strong, Moderate or Conditional recommendation grade was
assigned (based on degree of benefit-harm).
• Guidelines were evaluated by 49 independent reviewers