Page 14 - Flipbook

The first and last line concept

• The treatment of early-stage prostate cancer

remains controversial, especially for tumors

detected by means of prostate-specific antigen

(PSA) testing.

• We conducted a randomized trial to compare

radical prostatectomy with observation in 731 men

who had received a diagnosis of clinically localized

prostate cancer in the early era of PSA testing.