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U.S. PLCO (Prostate, Lung, Colorectal, and Ovarian)
Cancer Screening Trial
• 76,685 men aged 55-74 years
• annual screening for 6 years or “usual care”
• median f/u of 13 years by 2009
• The cumulative incidence rate for PCa was slightly higher in the
screened group with no difference in PCa mortality
N Engl J Med 2009;360:1310-9