Page 8 - Presentation
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Prostate Specific Membrane Antigen
• PSMA
– expression in almost all
PCa.
– increases with disease
grade
– PSMA binders with good
biodistribution have been
developed
• e.g. MP1404, DCPPyL,
68Ga-PSMA-HBED-CC and
others
– PCa tracers in Phase-III
trials
– Can be labeled to Gallium-
68, Fluor 18 or Technicium
99
Haberkorn et al. 2011 Oncogene
Haberkorn Clin Cancer Research 2016