Page 8 - Presentation
P. 8

Prostate Specific Membrane Antigen






                                                                                              • PSMA


                                                                                                     – expression in almost all
                                                                                                          PCa.

                                                                                                     – increases with disease
                                                                                                          grade

                                                                                                     – PSMA binders with good

                                                                                                          biodistribution have been
                                                                                                          developed

                                                                                                             • e.g. MP1404, DCPPyL,
                                                                                                                68Ga-PSMA-HBED-CC and
                                                                                                                others

                                                                                                     – PCa tracers in Phase-III
                                                                                                          trials

                                                                                                     – Can be labeled to Gallium-

                                                                                                          68, Fluor 18 or Technicium
                                                                                                          99








                                                                                                             Haberkorn et al. 2011 Oncogene
                                                                                                             Haberkorn Clin Cancer Research 2016
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