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418 CUAJ %u2022 DECEMBER 2024 %u2022 VOLUME 18, ISSUE 12 Chung et ality, affecting variables such as degree of hydronephrosis and nodal status and limiting our results. Furthermore, we acknowledge multifocality is an important prognosticator; however, given the limitations inherent to relying on radiology reports, this information was not able to be reliably captured. Given the variability and inconsistent reporting, certain radiographic findings, such as periureteral invasion suggestive of invasive disease and tumor size, were not included in this study. There is also the possibility of selection bias, as only candidates for surgical intervention were included and patients with missing preoperative radiographic findings were not included.We were also unable to assess other variables that may have had a role in the pathologic outcome, including delay from diagnosis to surgery, biopsy grade, tumor size on imaging, tumor multifocality, and other clinical factors. CONCLUSIONSAt multiple institutions in Manitoba, preoperative radiologic factors, such as hydronephrosis and tumor location, were not significant predictors of T2 disease or higher; however, further larger- scale studies are required to elucidate the role of preoperative radiologic findings in predicting pathologic outcomes.COMPETING INTERESTS: The authors do not report any competing personal or financial interests related to this workThis paper has been peer reviewed.REFERENCES1. Cho KS, Hong SJ, Cho NH, Choi YD. Grade of hydronephrosis and tumor diameter as preoperative prognostic factors in ureteral transitional cell carcinoma. Urology2007;70:662-666. https://doi.org/10.1016/j.urology.2007.06.11062. Ito Y, Kikuchi E, Tanaka N, et al. Preoperative hydronephrosis grade independently predicts worse pathological outcomes in patients undergoing nephroureterectomy for upper tract urothelial carcinoma. J Urol 2011;185:1621-1626. https://doi.org/10.1016/j.juro.2010.12.0353. 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Prognostic value of preoperative hydronephrosis in patients undergoing radical nephroureterectomy for upper tract urinary carcinoma: A systematic review and meta-analysis. Front Oncol 2020;10. https://doi.org/10.3389/fonc.2020.6005117. Qian S, Liang C, Ding Y, et al. Preoperative hydronephrosis predicts adverse pathological features and postoperative survival in patients with high-grade upper tract urothelial carcinoma. Int Braz J Urol 2021;47:159-68. https://doi.org/10.1590/s1677-5538.ibju.2020.00218. Hurel S, Roupr%u00eat M, Seisen T, et al. Influence of preoperative factors on the oncologic outcome for upper urinary tract urothelial carcinoma after radical nephroureterectomy. World J Urol 2015;33:335-41. https://doi.org/10.1007/s00345-014-1311-89. Kaczmarek K, Lemi%u0144ski A, Go%u0142%u0105b A, et al. Survival differences of patients with ureteral versus pelvicalyceal tumors: A systematic review and meta-analysis. Arch Med Sci2021;17:603-12. https://doi.org/10.5114/aoms.2019.8989310. Lee H-Y, Li C-C, Huang C-N, et al. Prognostic significance of lymphovascular invasion in upper urinary tract urothelial carcinoma is influenced by tumor location. Ann Surg Oncol2015;22:1392-1400. https://doi.org/10.1245/s10434-014-4103-x11. Waseda Y, Saito K, Ishioka J, et al. Ureteral involvement is associated with poor prognosis in upper urinary tract urothelial carcinoma patients treated by nephroureterectomy: A multicenter database study. Eur Urol Focus 2016;2:296-302. https://doi.org/10.1016/j.euf.2015.10.00812. Lwin AA, Hsu C-H, Chipollini J. Urothelial carcinoma of the renal pelvis and ureter: Does location make a difference? Clin Genitourin Cancer 2020;18:45-49.e1. https://doi.org/10.1016/j.clgc.2019.10.02313. Williams AK, Kassouf W, Chin J, et al. Multifocality rather than tumor location is a prognostic factor in upper tract urothelial carcinoma. 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Degree of hydronephrosis predicts adverse pathological features and worse oncologic outcomes in patients with high-grade urothelial carcinoma of the upper urinary tract. Urol Oncol 2014;32:981-8. https://doi.org/10.1016/j.urolonc.2014.02.01818. Wang LJ, Wong YC, Ng KF, et al. Tumor characteristics of urothelial carcinoma on multidetector computerized tomography urography.%u00a0J Urol%u00a02010;183:2154%u201360.%u00a019. Cowan NC, Turney BW, Taylor NJ, et al. Multidetector computed tomography urography for diagnosing upper urinary tract urothelial tumor.%u00a0BJU Int%u00a02007;99:1363-70.CORRESPONDENCE: Dr. David Chung, Section of Urology, Department of Surgery, University of Manitoba, Winnipeg, MB, Canada; chungt3@myumanitoba.ca