Page 4 - Metastatic castration-naive and castration-sensitive prostate cancer: CUA/CUOG
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Methods








          • MEDLINE and Embase were searched from January 2000 to August 2019


          • An expert panel comprised of urologists, medical oncologists, and

               radiation oncologists with significant experience managing mCNPC/mCSPC

               was used to develop the recommendations

          • Levels of evidence and grades of recommendation employ the ICUD/WHO

               modified Oxford Center for Evidence-Based Medicine grading system


                 – Wherever Level 1 evidence is lacking, the guideline provides expert opinion

          • The strength of each recommendation is represented by the words

               STRONG or WEAK



          ICUD: International Consultation on Urologic Diseases; mCNPC: metastatic castration-naive prostate cancer;
          mCSPC: metastatic castration-sensitive prostate cancer; WHO: World Health Organization
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