Page 3 - Diagnosis and management of radiation-induced hemorrhagic cystitis
P. 3
Definitions
• Hemorrhagic cystitis refers to a collection of symptoms and signs
defined by hematuria, lower urinary tract symptoms, and cystoscopic
findings indicative of underlying urothelial damage.
• It can have a number underlying causative factors, including treatment
with chemotherapeutic agents, such as cyclophosphamide and
concurrent therapies, post-transplant patients, infection-mediated, as
well as treatment with radiation therapy.
• Radiation-induced hemorrhagic cystitis (RHC) is often an adverse
event in patients with previous radiation to the pelvis for urological or
gynecological malignancy and is the focus of this best practice report.
