Page 2 - Male Hormone Replacement

Male hormone replacement
brain
cardiovascular
muscle system
liver
prostate
penis testicle
bone
Roula Drossis
Changes in risk factors for heart and blood vessel
disease have been identified with the use of
testosterone supplementation; some are thought to
be beneficial and some unfavourable. The overall
effect of these changes is unclear.
Blood levels of hemoglobin (the oxygen-carrying
component of blood) may rise, possibly increasing the
risk of blood clots. In men with sleep apnea (pauses
in breathing while asleep), the problem may worsen
while on testosterone replacement therapy.
This publication is produced by
The information in the publication is not intended to convey medical advice or to substitute for direct consultation with a qualified medical
practitioner. The Canadian Urological Association disclaims all liability and legal responsibility howsoever caused, including negligence, for the
information contained in or referenced by this brochure.
© 2014. Canadian Urological Association. All rights reserved.
Testosterone may promote prostate enlargement
and an increase in PSA level (the blood test used to
help detect prostate cancer). No clear link has been
demonstrated between testosterone replacement
and prostate cancer or the development of voiding
difficulty from prostate enlargement.
It has been recommended that men on testosterone
supplementation be monitored regularly, which may
include blood tests, for these problems during the first
year of treatment and then at least yearly afterwards.
How do I take testosterone?
Testosterone supplementation is available in a
number of forms. Although no form of testosterone
supplementation can mimic the normal hourly and
day-to-day variations in hormone secretion by the
testicles, testosterone levels can be reliably increased
by injection (typically every few weeks) or the daily
application of a skin patch, gel, underarm solution
or cream. Tablets, although convenient, may be less
reliable at restoring a normal testosterone level.
The significance of normal testosterone reduction with
age and the role of testosterone supplementation
therapy can be confusing. Replacement therapy can
be beneficial but it requires regular monitoring for the
detection of any adverse effects. These issues should
be considered and discussed with your physician.
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