Page 7 - PRESENTATION
P. 7

Risk Adapted Treatment of NMIBC













                                        Transurethral resection of bladder tumor (TURBT) + Single dose chemo


                                                                         Stratification into risk group

                                        Low risk                              Intermediate risk                                      High risk                             Consider early

                    treatment          + cytology                              1yr maintenance                                      BCG for 3yr                           T1HG, or T1 with
                1L          Monitoring via cystoscopy                   BCG or chemo. induction +                                Repeat TURBT                               cystectomy if:
                                                                                                                                                                            T1HG + CIS,
                                                                                                                                                                            multiple/large


                                                                                                                                                                          variant histology
                   treatment                                              Switch to BCG or chemo                           GEM/DOC                 Radical                  RC for HG T1
                                                                                                                            Consider
                2L                                                      depending on 1L treatment                         BCG/IFN, etc           Cystectomy                    eligible
                                                                                                                                                                            recurrence if




                   treatment                                                                                              BCG/IFN, etc           Cystectomy                    eligible
                                                                                                                            Consider
                                                                                                                                                                              RC for all
                3L                                                       Alternative chemotherapy                          GEM/DOC                 Radical                    patients if
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