Page 19 - New Treatment Options for Adults and Children with Overactive Bladder

Antimuscarinics in Canada

Generic name Trade name Dose supplied Recommended dose

5 mg 2-3 times per day, up to 4 times
Oxybutynin Generic 2.5 mg, 5mg, 10 mg
per day
Transdermal Oxytrol 3.9 mg 3.9mg per day (twice weekly)
oxybutynin Gelnique 10% solu’n 100mg) Daily
Dose escalation from
Oxybutynin ER Ditropan XL 5 mg, 10 mg
5 mg to 30 mg once daily
Tolterodine IR Detrol 1 mg, 2 mg 1 or 2 mg twice a day

Tolterodine ER Detrol LA 2 mg, 4 mg 2 or 4 mg once daily

Dose escalation from 5 to 10 mg once
Solifenacin Vesicare 5 mg, 10 mg
daily
Dose escalation from 7.5 to 15 mg once
Darifenacin Enablex 7.5 mg, 15 mg
daily
IR 20 mg 20 mg twice daily
Trospium
Sanctura XR 30 mg 30 mg once daily
Dose escalation from 4 to 8 mg once
Fesoterodine Toviaz 4mg, 8 mg
daily
Propiverine Mictoryl 30mg, 45mg Daily dose

Combined Non-specific M3 Specific