Page 11 - 2020 ASCO-GU Canadian Ambassador Program

BACKGROUND & STUDY RATIONALE

• Conventional imaging modalities are suboptimal for staging

or re-staging men at risk of harbouring occult mPCa

• 18 F-FDG PET/CT is not accurate to stage/re-stage mPCa

• Metabolism-associated PET tracers have been developed to

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improve PET/CT accuracies (e.g. F-DCFPyL)

• To date, only retrospective studies have been published

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• There is a need to validate F-DCFPyL PET/CT in

prospective, multicentre, controlled, multi-blinded and

independent central reader studies