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Definition and Criteria for Grading Cancer Anemia

Grade of Anemia CTCAE Criteria

Grade 1 Hemoglobin (Hgb) <LLN - 10 g/dL

Grade 2 Hgb <10 – 8 g/dL

Grade 3 Hgb <8 g/dL; transfusion indicated

Grade 4 Life-threatening consequences; urgent intervention indicated

Grade 5 Death

Common Terminology Criteria for Adverse Events (CTCAE). Available at:
https://ctep.cancer.gov/protocolDevelopment/electronic_applications/ctc.htm#ctc_50.