Page 7 - FLIPBOOK

• 21/ 1990 studies for qualitative synthesis

• Examined the impact of Ach drug use >=3 mos on dementia/ cog impairment

• RCT, case-control or cohort study
• Adequate description of methodology

• Primary publication

• 6 of these met criteria for meta-analysis for outcome of incident dementia

• Contained comparison group, reported appropriate relative effect measure estimates or
summary statistics to derive estimates

• 3 case-control and 3 cohort studies with data from 645,865 patients across 5

countries