Page 9 - Flipbook
P. 9

AVAILABLE HORMONAL THERAPIES FOR PC TREATMENT









                  • Surgical castration



                  • Medical castration


                         • Gonadal androgen ablation


                                • LHRH agonists: leuprolide, goserelin, and triptorelin

                                • LHRH antagonists: degarelix, relugolix


                  • Androgen receptor antagonists (AA)



                                • First generation: bicalutamide

                                • Second generation: enzalutamide, apalutamide and darolutamide


                  • Androgen synthesis inhibitors (CYP17 adrenal inhibitors):


                      abiraterone acetate, ketoconazole











                  LHRH Luteinizing hormone-releasing hormone                                                                      Kokorovic A, et al. CUAJ 2021 April 21; Epub ahead of print.
   4   5   6   7   8   9   10   11   12   13   14