Page 6 - CUA Presentation
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Germline BRCA Mutations







                                                                                                       Cancer Risk





                                                          General Population                                     BRCA1                                    BRCA2




                Female breast                                       11-12%                                        >60%                                     >60%



                Ovarian                                               1-2%                                     39%-58%                                  13%-29%




                Prostate                                          11-12%                                         21%      1                               27%      1




                Male breast                                           <1%                                      elevated                                 Up to 8%



                Pancreas                                              <1%                                          ≤5%                                   5%-10%







                                                                       Risks are considered Lifetime Risk; 1, absolute risk to age 75









                                                                           National Comprehensive Cancer Network® (NCCN®) Version 2.2022
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