Page 10 - FLIPBOOK
P. 10
Study introduction and objectives
• Androgen Deprivation Therapy (ADT) is standard of Objectives of study included:
care for Advanced Prostate Cancer (PCa) – evaluation of timeliness
of ADT dosing
• Luteinizing Hormone-Releasing Hormone (LHRH)
agonists are widely used to suppress serum – impact of non-adherence
Testosterone (T) to castration levels on T levels
• Current castration level is T <50 ng/dl, however recent – frequency of T and PSA testing
evidence suggests <20 ng/dl is closer to postoperative in patients with PCa
castration
• ADT effectiveness in clinical practice relies on
adherence to dosing schedule, correct mixing and
administration, and periodic T monitoring
• healthcare providers and patients may be
unaware of potential consequences of even
a short delay in dosing
SOURCE: Crawford E.D. et al.,The Journal of Urology. Vol. 203, 743-750, April 2020.