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mCSPC












                Can be rapidly lethal




                Occurs either the de novo (synchronous)/recurrent (metachronous) setting


                In those at high risk of disease progression, overall survival with ADT monotherapy


                is approximately 3 years













                 Since 2013, multiple pivotal trials have shown that ADT alone is NOT enough and

                   patients should receive early intensification beyond ADT either by docetaxel or

                                                                          novel hormonal agents
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