Page 9 - Flipbook
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DFS by Sarcomatoid Histology Status Subgroups
Sarcomatoid Features Absent Sarcomatoid Features Present
100 24-mo rate 100 24-mo rate
90 79.5% HR 0.63 (95% CI 0.48−0.83) 90 HR 0.54 (95% CI 0.29–1.00)
80 80 71.8%
70 70
69.4% 60
60
DFS, % 50 DFS, % 50 52.0%
40
30 40
30
20 20
Pembro Pembro
10 10
Placebo Placebo
0 0
0 5 10 15 20 25 30 35 40 45 50 0 5 10 15 20 25 30 35 40 45 50
Months Months
No. at risk No. at risk
Pembro 414 385 350 327 305 216 117 67 32 0 0 Pembro 52 48 41 37 34 27 11 5 3 0 0
Placebo 415 367 331 304 277 201 110 68 30 1 0 Placebo 59 48 40 35 33 21 12 4 3 0 0
Pts w/ Event Median, mo (95% CI) Pts w/ Event Median, mo (95% CI)
Pembro 88 NR (NR–NR) Pembro 16 NR (NR–NR)
Placebo 133 NR (NR–NR) Placebo 29 40.5 (11.3–NR)
DFS, disease-free survival; NR, not reached. Data cutoff date: June 14, 2021.
