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       many years after surgery and are seen more frequently in   9.  Plouin PF, Gimenez-Roqueplo AP. Initial workup and long-term followup in patients with pheo -
                                                                chromocytomas and paragangliomas. Best Pract Res Clin Endocrinol Metab 2006a;20:421-34.
       patients with a genetic disease, young age, large tumor, and   https://doi.org/10.1016/j.beem.2006.07.004
       extra-adrenal disease. All patients should be considered for   10.  Hamidi O, Young WF Jr, Iniguez-Ariza NM, et al. Malignant pheochromocytoma and paraganglioma:
       genetic testing. Patients should be screened with plasma and   272 patients over 55 years. J Clin Endocrinol Metab 2017;102:3296-305. https://doi.org/10.1210/
       urinary metanephrines postoperatively, and yearly thereafter   jc.2017-00992
       for at least 10 years, and potentially indefinitely for higher-  11.  Favier J, Amar L, Gimenez-Roqueplo AP. Paraganglioma and pheochromocytoma: From genetics to per-
                                                                sonalized medicine. Nat Rev Endocrinol 2015;11:101-11. https://doi.org/10.1038/nrendo.2014.188
       risk patients.                                        12.  Eisenhofer G, Peitzsch M. Laboratory evaluation of pheochromocytoma and paraganglioma. Clin Chem
         A summary of all BPR recommendations is shown in       2014;60:1486-99. https://doi.org/10.1373/clinchem.2014.224832
       Table 1.                                              13.  Lenders JW, Keiser HR, Goldstein DS, et al. Plasma metanephrines in the diagnosis of pheochromocytoma.
                                                                Ann Intern Med 1995;123:101-9. https://doi.org/10.7326/0003-4819-123-2-199507150-00004
       Competing interests: Dr. Violette has been a speakers’ bureau member for Janssen and Sanofi (no   14.  Lenders JW, Pacak K, Walther MM, et al. Biochemical diagnosis of pheochromocytoma: Which test is
       honoraria). Dr. Tomiak has received speaker honoraria from AstraZeneca. Dr. Izard has received   best? JAMA 2002;287:1427-34. https://doi.org/10.1001/jama.287.11.1427
       advisory board and consulting fees from Abbvie, Astellas, Ferring, Janssen, and Sanofi; and has   15.  Perry CG, Sawka AM, Singh R, et al. The diagnostic efficacy of urinary fractionated metanephrines measured
                                                                by tandem mass spectrometry in detection of pheochromocytoma. Clin Endocrinol (Oxf) 2007;66:703-8/
       participated in clinical trials supported by Astellas, AstraZeneca and Merck. Dr. Rowe has participated   https://doi.org/10.1111/j.1365-2265.2007.02805.x
       in an advisory board meeting for Acerus and has received honoraria from Sanofi. The remaining   16.  Amar L, Lussey-Lepoutre C, Lenders JW, et al. Recurrence or new tumors after complete resection of
       authors report no competing personal or financial interests related to this work.  pheochromocytomas and paragangliomas: A systematic review and meta-analysis.  Eur J Endocrinol
                                                                2016;175:R135-45. https://doi.org/10.1530/EJE-16-0189
                                                             17.  Plouin PF, Amar L, Dekkers OM, et al. European Society of Endocrinology clinical practice guideline for
       Prior to publication, this BPR underwent review by the CUA Guidelines Committee, CUA members   long-term followup of patients operated on for a pheochromocytoma or a paraganglioma. Eur J Endocrinol
       at large, the CUAJ Editorial Board, and the CUA Executive Board.  2016;174:G1-0. https://doi.org/10.1530/EJE-16-0033
                                                             18.  Eisenhofer G, Goldstein DS, Walther MM, et al. Biochemical diagnosis of pheochromocytoma: How
                                                                to distinguish true- from false-positive test results.  J Clin Endocrinol Metab 2003b;88:2656-66.
                                                                https://doi.org/10.1210/jc.2002-030005
                                                             19.  Algeciras-Schimnich A, Preissner CM, Young WF Jr, et al. Plasma chromogranin A or urine fractionated
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