Page 20 - Flipbook

LARGE OBSERVATIONAL COHORT STUDIES DESCRIBE A STRONG

LINK BETWEEN ADT AND CVD

• Meta-analysis including 119,000 PC patients receiving ADT 1

• Use of ADT associated with a significant risk of CV mortality

(HR 1.17; 95% CI 1.04–1.32)

• Meta-analysis of 8 observational studies 2

• 38% increase in nonfatal CVD for men treated with an LHRH agonist

(RR 1.38; 95% CI 1.29–1.48)

1. Zhao J, et al. PLoS One 2014;9:e107516 2. Bosco C, et al. Eur Urol 2015;68:386-96