Page 22 - Flipbook
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IS THERE A DIFFERENT RISK PROFILE FOR AGONISTS VERSUS
ANTAGONISTS?
• Pooled analysis of 6 RCTs found that men with pre-existing
CVD treated with a GnRH antagonist (compared to agonist)
were 56% less likely to have a CV event within 1 year of
beginning ADT
• Studies have several limitations and results remain
controversial
RCT Randomized, controlled trial Albertsen PC, et al. Eur Urol 2014;65:565-73
