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Adjuvant BEP x 1 for Stage I NSGCT
• 246 CSI NSGCT with lymphovascular invasion (CSIB)
• Single-arm study: all received BEP x 1
• Primary end-point: “malignant recurrence at 2 years”
• Secondary end-point: “benign recurrence”
• E.g. Teratoma
• Median follow-up: 49 months
Results: Malignant Recurrence @ 2yrs: 1.3%
Conclusions: Adoption of BEPx1 as standard
would reduce overall exposure to chemo