Page 8 - CUAJ Dec. 2022
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CHOOSE XTANDI.




         mCSPC                         mCRPC                                   nmCRPC
         Pr XTANDI® (enzalutamide     XTANDI is indicated in the setting      XTANDI is indicated for the treatment
         capsules) is indicated       of medical or surgical castration       of patients with non-metastatic
         for the treatment of         for the treatment of metastatic         castration-resistant prostate cancer
         patients with metastatic     castration-resistant prostate           (nmCRPC). XTANDI has not been
         castration-sensitive prostate   cancer (mCRPC) in patients who:      studied in patients with nmCRPC
         cancer (mCSPC).              •  are chemotherapy-naïve with          at low risk of developing metastatic

                                        asymptomatic or mildly symptomatic    disease. The bene…t and risk pro…le

                                        disease after failure                 in these patients is unknown.
                                        of androgen deprivation therapy.
                                      • have received docetaxel therapy.






























                                                                                                   LEARN MORE

        Please consult the product monograph at https://www.astellas.com/ca/system/…les/xtandi_

        pm_jan_24_2022-…nal_en.pdf or call 1-888-338-1824 for important information relating to:

        • Contraindications in women who are or may become pregnant, or who are lactating
        •  The most serious warnings and precautions regarding seizures and Posterior Reversible
         Encephalopathy Syndrome (PRES)
        •  Other relevant warnings and precautions regarding hereditary fructose intolerance,
         cytochrome P450 interactions and dose adjustments, carcinogenic potential, cardiovascular
         events (including ischemic heart disease, QTc prolongation and hypertension), hypersensitivity
         reactions, non-pathological bone fractures or falls and fall-related injuries, neuropsychiatric
         adverse events, mental impairment disorders, use of contraception, potential e—ects on male

         fertility, recommendations in severe renal impairment or end-stage renal disease and monitoring
         in nmCRPC patients
        • Conditions of clinical use, adverse reactions, interactions and dosing
                                                                 
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                                                                                         MEMBRE DE


   23079j_XTANDI_1PgChooseXTANDCUAJ Journal AdEN_REL_C00_00_.indd   1                                     2022-09-22   2:58 PM
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