Page 3 - CUA Adv Prostate Ca Drug Acccess Listing
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ALBERTA                                                                                                                                                 Link to Patient Assistance Programs


                            Funding:
                            Cancer patients may receive treatment at cancer centres, their community hospitals, or taken at home.
                            Alberta provides cancer drugs specified in the Outpatient Cancer Drug Benefit Program, at no charge, to eligible residents for the treatment of cancer.

                            Formulary:
                            Alberta Health Services https://www.albertahealthservices.ca/assets/programs/ps-1025651-drug-benefit-list.pdf


                             DRUG                                 Strength,                                                                                                                       References
                             (Brand Name)       Indication                       DIN††         Provincial Funding Eligibility Criteria
                             Manufacturer                         Route
                                                                                               Group 2*                                                                                           AB Cancer
                                                                                                                                                                                                  Outpatient Drug
                             Abiraterone                                                       Eligibility:                                                                                       Benefit Program
                             (Zytiga)           mCRPC             Oral           Multiple      •    Patients with mCRPC                                                                           [9-21]
                             Janssen
                                                                                               •    Patients with mCRPC, following ( progression on or intolerance to) apalutamide,
                                                                                                    enzalutamide, or darolutamide use in nmCRPC setting
                                                                                                                                                                                                  AB BlueCross
                                                                                                               1
                             Alendronate        Osteoporosis      70 mg PO       Multiple      Regular Benefit : No form required
                                                                                                                                                                                                  Drug Benefit List
                                                                                               Group 2*                                                                                           AB Cancer
                                                                                                                                                                                                  Outpatient Drug
                                                                                               Eligibility:                                                                                       Benefit Program
                                                                                               •    In combination with ADT for the treatment of patients with nmCRPC                             [9-21]
                                                                                                         o   No detectable distant metastases by either CT, MRI, or technetium-99m bone
                                                                                                             scan
                                                                                                                                                                          †
                                                                                                         o   At high risk of developing metastases (PSADT ≤ 10 months )
                                                                                 Not                     o   CRPC demonstrated during continuous ADT/post orchiectomy
                             Apalutamide        nmCRPC            Oral           specified               o   Minimum of 3 rising PSA values at an interval or ≥ 1 week apart with a
                             (Erleada)                                                                       last PSA > 2 ng/mL
                             Janssen                                                                     o   Maintain castrate levels of testosterone throughout apalutamide therapy
                                                                                               •    Patients treated with prior chemotherapy in the adjuvant or neoadjuvant setting are
                                                                                                    eligible
                                                                                               •    Patients may receive only one of these agents (darolutamide, apalutamide or
                                                                                                    enzalutamide) in this setting and switching only if intolerance, not progression to one
                                                                                                    agent
                                                                                 Not                                                                                                               Provincial Funding
                                                mCSPC             -                            Under negotiation with manufacturer
                                                                                 specified                                                                                                         Summary [10-20]
                                                                                               Group 2*                                                                                            AB Cancer
                                                                                                                                                                                                   Outpatient Drug
                             Darolutamide                                        Not           Eligibility:                                                                                        Benefit Program
                             (Nubeqa)           nmCRPC            Oral           specified     •    In combination with ADT for the treatment of patients with nmCRPC                              [9-21]
                             Bayer                                                             •    At high risk of developing metastases (PSADT ≤ 10 months  during continuous ADT)
                                                                                                                                                                 †
                                                                                               •    Patients may receive only one of these agents (darolutamide, apalutamide or
                                                                                                    enzalutamide) in this setting and switching only if intolerance, not progression









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