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Tissue Testing For Molecular Assessment Is Currently Recognized As the


     Gold Standard for Tumour Analysis                                                   1,2,6






                                                                               Molecular testing



                                                                               To determine patient:        5

                                                                                    Prognosis


                                                                                    Familial risk

                                                                                    Treatment decision









                                            Plasma                                        Tissue                                       Blood



                                  High potential but clinical                More established and widely
                                                                                                                             Unable to detect somatic
                                validation in prostate cancer               used approach in various cancer
                                    currently very limited  6                             types 3,4                                  mutations



                               Proven tool in lung when tissue                Can detect both germline &
                                        is unavailable  7                          somatic mutations    5





      1. Lindeman N et al. J Thoracic Oncol 2018;13:323-58; 2. Kim L, Tsao MS. Eur Respir J 2014;44:1011-22; 3. Ma M et al. Gene 2016;591:58-64; 4. Wang Y et al. Oncol Lett 2017;13:2425-31;
      5. Cheng H et al. ASCO Ed Book 2018:372-81; 6. Boerrigter E et al. Exp Rev Mol Diagnostics 2020;20:219-30; 7. Arriola E et al. Clin Trans Oncol 2018;20:1261-67.
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