Page 15 - Flipbook
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Tissue Testing For Molecular Assessment Is Currently Recognized As the
Gold Standard for Tumour Analysis 1,2,6
Molecular testing
To determine patient: 5
Prognosis
Familial risk
Treatment decision
Plasma Tissue Blood
High potential but clinical More established and widely
Unable to detect somatic
validation in prostate cancer used approach in various cancer
currently very limited 6 types 3,4 mutations
Proven tool in lung when tissue Can detect both germline &
is unavailable 7 somatic mutations 5
1. Lindeman N et al. J Thoracic Oncol 2018;13:323-58; 2. Kim L, Tsao MS. Eur Respir J 2014;44:1011-22; 3. Ma M et al. Gene 2016;591:58-64; 4. Wang Y et al. Oncol Lett 2017;13:2425-31;
5. Cheng H et al. ASCO Ed Book 2018:372-81; 6. Boerrigter E et al. Exp Rev Mol Diagnostics 2020;20:219-30; 7. Arriola E et al. Clin Trans Oncol 2018;20:1261-67.