Page 10 - FLIPBOOK
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ADT is Foundational in the Treatment of Advanced


                Prostate Cancer








                   • Prostate cancer is primarily


                       androgen dependent



                   • Primary ligand is T

                                                                                                                                                 MED
                   • Goal is to lower and maintain T


                       to castrate levels and/or block


                       activity at AR



                   • Maximally deprive tumour                                                                              LOW                                     HIGH


                       environment of T                                                                                      Testosterone Levels



                   • There is a range of therapeutic

                       options for effective ADT







                                                                                                                               Crawford ED, et al. Prostate Cancer Prostatic Dis 2019;22:24–38
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