Page 11 - FLIPBOOK
P. 11

Goals of ADT











            • Achieve and maintain an                                                               • Achieve and maintain low nadir T

                environment of low T activity                                                       • Personalize


                   • Suppress T to “castrate levels”                                                       • Tailor to patients’ lifestyles and

                       and/or                                                                                  schedules

                   • Effectively block AR                                                           • Minimize side effects


            • Rapid onset of T suppression                                                          • Consider cost



            • Block effect of T surge if relevant                                                   • Improve patient outcomes


            • Reduce T to < 0.7 nmol/L                                                                     • Reduce morbidity


                (< 20 ng/dL)                                                                               • Extend survival


            • Consistent T suppression


                   • No escapes or microsurges while

                       on treatment




                                                                                                                            Crawford ED, et al. Prostate Cancer Prostatic Dis 2019;22:24–38
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