Page 7 - Guideline

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Management of testicular germ cell cancer

Table 5. Summary of surveillance studies in stage I nonseminoma

Author (publication year) Years of No. Median Relapses, Deaths, DSS
Site study patients follow-up (mo) no. (%) no. (%)
Sturgeon [personal communication] 1981-2005 371 76 104 (28%) 3 (1%) 99%
(2008) Princess Margaret Hospital, Toronto
Divrik (2006) 49 1993-2005 211 75 66 (31%) 5 (2%) 98%
Ankara
Daugaard (2003) 13 1984-2001 301 60 86 (29%) 0 (0%) 99%
Copenhagen
Roeleveld (2001) 50 1982-1994 90 97 23 (26%) 1 (1%) 99%
Amsterdam
Alexandre (2001) 51 1984-1996 88 52 24 (27%) 1 (1%) 98%
France
Francis (2000), Londo 52 1979-1996 183 70 52 (28%) 2 (1%) 99%

Sogani (1998) 53 1979-1987 105 136 27 (26%) 3 (3%) 97%
Memorial Sloan-Kettering Cancer Center, NY
Colls (1999) 46 1980-1997 248 53 70 (28%) 4 (2%) 98%
New Zealand
Hao (1998) 54 1980-1994 76 49 28 (37%) 2 (3%) 97%
Tom Baker Cancer Centre, Calgary
Boyer (1997) 55 1982-1995 77 58 27 (35%) 2 (3%) 97%
Australia
Nicolai (1995) 56 1981-1984 85 132 25 (29%) 3 (4%) 96%
Milan
Gels (1995) 57 1982-1992 154 84 42 (27%) 2 (1%) 99%
Groningen
Ondrus and Hornak (1994) 58 1984-1993 80 83 29 (36%) 4 (5%) 95%
Slovak Republic
Read (1992) 45 1984-1987 373 60 100 (27%) 5 (1%) 98%
17
United Kingdon, Denmark 1
Freedman (1987) 59 1979-1983 259 30 70 (27%) 3 (1%) 98%
United Kingdom multicentre
Pooled data 1979-2005 2701 30-136 773 (28.6%) 40 (1.5%)

Maroto* (2005) 60 1994-2004 358 40 71 (20%) 5 (1.4%) 95%
Spanish Germ Cell Group
Amato* (2004) 61 1993-1999 23 38 3 (13%) 0 (0%) 100%
M.D. Anderson Cancer Center, Houston
Ondrus* (1998) 62 1992-1997 49 37 7 (14.3%) 0 (0%) 100%
Slovak Republic
Klepp* (1997) 48 1990-1994 106 40 23 (22%) 0 (0%) 100%
Sweden-Norway (Swedish-Norwegian
Testicular Cancer Project)
Pont* (1990) 47 1985-1989 22 30 1 (4.5%) 0 (%) 100%
Vienna
Rorth** (1991) 63 1980-1984 77 64 23 (30%) 0 (0%) 100%
Danish Testicular Cancer Study Group
*= indicates single arm of a risk-adapted study; ** = indicates single arm of a randomized trial; DSS = disease-specific survival.

CUAJ • April 2010 • Volume 4, Issue 2 E25